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Progeria

6/24/2013

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We are all afraid to get old, the world is still searching for the fountain of youth to unlock the secret of aging.

Hutchinson Gilford Progeria Syndrome, or Progeria syndrome) is an extremely rare genetic disease wherein symptoms resembling aspects of aging are manifested at a very early age. The word progeria comes from the Greek words "pro", meaning "before" or "premature", and "gēras" (γῆρας), meaning "old age". The disorder has a very low incident rate, occurring in an estimated 1 per 8 million live births. Those born with progeria typically live to their mid teens and early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson-Gilford Progeria Syndrome (HGPS).


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Leptospirosis

6/13/2013

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The rainy season has come flood prone areas are again in high risks of Leptospirosis.

Leptospirosis is a bacterial disease that affects both humans and animals. Humans become infected through direct contact with the urine of infected animals or with a urine-contaminated environment. The bacteria enter the body through cuts or abrasions on the skin, or through the mucous membranes of the mouth, nose and eyes. Although more common in tropical areas, non-tropical urban conglomerations with low levels of sanitation are seeing more cases, especially during the summer and autumn months. Most of the urban areas affected involve large cities in the developing world.


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Diabetes Mellitus

11/23/2012

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Diabetes mellitus type 1 (type 1 diabetes, T1DM, formerly insulin dependent or juvenile diabetes) is a form of diabetes mellitus that results from autoimmune destruction of insulin-producing beta cells of the pancreas. The subsequent lack of insulin leads to increased blood and urine glucose. The classical symptoms are polyuria (frequent urination), polydipsia (increased thirst), polyphagia (increased hunger), and weight loss.

Incidence varies from 8 to 17 per 100,000 in Northern Europe and the U.S. with a high of about 35 per 100,000 in Scandinavia to a low of 1 per 100,000 in Japan and China.

Eventually, type 1 diabetes is fatal unless treated with insulin. Injection is the most common method of administering insulin although other methods are insulin pumps and inhaled insulin. Other alternatives are Pancreatic transplants that have been used and also pancreatic islet cell transplantation. Transplantation is experimental yet growing.


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Pancreatic Cancer 

11/17/2012

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Pancreatic cancer is a malignant neoplasm originating from transformed cells arising in tissues forming the pancreas. The most common type of pancreatic cancer, accounting for 95% of these tumors, is adenocarcinoma (tumors exhibiting glandular architecture on light microscopy) arising within the exocrine component of the pancreas. A minority arise from islet cells, and are classified as neuroendocrine tumors. The signs and symptoms that eventually lead to the diagnosis depend on the location, the size, and the tissue type of the tumor, and may include abdominal pain, lower back pain, and jaundice (if the tumor compresses the bile duct).

Pancreatic cancer is the fourth most common cause of cancer-related deaths in the United States and the eighth worldwide. Pancreatic cancer has a poor prognosis: for all stages combined, the 1- and 5-year relative survival rates are 25% and 6%, respectively; for local disease the 5-year survival is approximately 20% while the median survival for locally advanced and for metastatic disease, which collectively represent over 80% of individuals, is about 10 and 6 months respectively.


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Chikungunya Virus

10/19/2012

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Chikungunya fever is a viral disease transmitted to humans by the bite of infected Aedes Aegypti mosquitoes.

Chikungunya virus (CHIKV) is a member of the genus Alphavirus, in the family Togaviridae. CHIKV was first isolated from the blood of a febrile patient in Tanzania in 1953, and has since been identified repeatedly in west, central and southern Africa and many areas of Asia, and has been cited as the cause of numerous human epidemics in those areas since that time.

The virus circulates throughout much of Africa, with transmission thought to occur mainly between mosquitoes and monkeys.


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"Flesh Eating Disease"

8/28/2012

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Media reports have popularized the term "flesh-eating bacteria" to refer to a type of very rare but serious bacterial infection known as necrotizing fasciitis. Necrotizing fasciitis is an infection that starts in the tissues just below the skin and spreads along the flat layers of tissue (known as fascia) that separate different layers of soft tissue, such as muscle and fat. This dangerous infection is most common in the arms, legs, and abdominal wall and is fatal in 30%-40% of cases.

Although necrotizing fasciitis may be caused by an infection with one or more than one bacterium, in most cases the term flesh-eating bacteria has been applied to describe infections caused by the bacterium known as Streptococcus pyogenes. The term flesh-eating has been used because the bacterial infection produces toxins that destroy tissues such as muscles, skin, and fat. Streptococcus pyogenes is a member of the group A streptococci, a group of bacteria that are commonly responsible for mild cases of sore throat (pharyngitis) and skin infections, as well as rare, severe illnesses such as toxic shock syndrome and necrotizing fasciitis. Most infections with group A streptococci result in mild illness and may not even produce symptoms.


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